Articulos actualizados de medicina super interesantes! Martes, 19 de abril de 2011. La lesión fundamental de la enfermedad de Parkinson recae en la parte compacta de la sustancia nigra,. Que forma parte de los ganglios basales. En esta enfermedad se produce una desaparición progresiva de las neuronas dopaminérgicas del sistema nigroestriado, con despigmentación y consecuente gliosis, mientras que en las neuronas supervivientes aparecen los cuerpos de Lewy. 8226; Temblor, que es el primer síntoma en el 75.

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